Homo sapiens Gene: SMARCD3 | |||||||||||||||||||||||||||||
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Summary | |||||||||||||||||||||||||||||
InnateDB Gene | IDBG-49450.6 | ||||||||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||||||||
Gene Symbol | SMARCD3 | ||||||||||||||||||||||||||||
Gene Name | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 | ||||||||||||||||||||||||||||
Synonyms | BAF60C; CRACD3; Rsc6p | ||||||||||||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||||||||||||
Ensembl Gene | ENSG00000082014 | ||||||||||||||||||||||||||||
Encoded Proteins |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
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Protein Structure | |||||||||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||||||
Summary |
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||||||||
Genomic Location | Chromosome 7:151238764-151277896 | ||||||||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||||||||
Band | q36.1 | ||||||||||||||||||||||||||||
Transcripts | |||||||||||||||||||||||||||||
Interactions | |||||||||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||||||||
REACTOME |
PPARA activates gene expression pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Activation of gene expression by SREBF (SREBP) pathway
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
RORA activates circadian gene expression pathway
BMAL1:CLOCK,NPAS2 activates circadian gene expression pathway
REV-ERBA represses gene expression pathway
Circadian Clock pathway
YAP1- and WWTR1 (TAZ)-stimulated gene expression pathway
Generic Transcription Pathway pathway
Transcriptional regulation of white adipocyte differentiation pathway
Transmembrane transport of small molecules pathway
Organelle biogenesis and maintenance pathway
Developmental Biology pathway
Metabolism of lipids and lipoproteins pathway
Mitochondrial biogenesis pathway
Orphan transporters pathway
Transcriptional activation of mitochondrial biogenesis pathway
Chromatin organization pathway
RMTs methylate histone arginines pathway
Chromatin modifying enzymes pathway
Metabolism pathway
Gene Expression pathway
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KEGG | |||||||||||||||||||||||||||||
INOH | |||||||||||||||||||||||||||||
PID NCI |
LKB1 signaling events
Validated transcriptional targets of TAp63 isoforms
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Cross-References | |||||||||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||||||||
UniGene | Hs.647067 Hs.649478 | ||||||||||||||||||||||||||||
RefSeq | NM_001003801 NM_001003802 NM_003078 | ||||||||||||||||||||||||||||
HUGO | |||||||||||||||||||||||||||||
OMIM | |||||||||||||||||||||||||||||
CCDS | CCDS34780 CCDS5924 | ||||||||||||||||||||||||||||
HPRD | 03440 | ||||||||||||||||||||||||||||
IMGT | |||||||||||||||||||||||||||||
EMBL | |||||||||||||||||||||||||||||
GenPept | |||||||||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||||||||