Version 5.4
Homo sapiens Gene: MYF5
Summary
InnateDB Gene IDBG-49657.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYF5
Gene Name myogenic factor 5
Synonyms bHLHc2
Species Homo sapiens
Ensembl Gene ENSG00000111049
Encoded Proteins
IDBP-49659
myogenic factor 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:80716912-80719673
Strand Forward strand
Band q21.31
Transcripts
ENST00000228644 ENSP00000228644
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
GO:0046982 protein heterodimerization activity
GO:0046983 protein dimerization activity
GO:0070888 E-box binding
Biological Process
GO:0001502 cartilage condensation
GO:0001503 ossification
GO:0001756 somitogenesis
GO:0001952 regulation of cell-matrix adhesion
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0007517 muscle organ development
GO:0007519 skeletal muscle tissue development
GO:0030198 extracellular matrix organization
GO:0035914 skeletal muscle cell differentiation
GO:0042692 muscle cell differentiation
GO:0042693 muscle cell fate commitment
GO:0043010 camera-type eye development
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048644 muscle organ morphogenesis
GO:0048704 embryonic skeletal system morphogenesis
GO:0051149 positive regulation of muscle cell differentiation
GO:0060415 muscle tissue morphogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000000435
View Gene Order
ENSBTAG00000026972
Not yet available
Pathways
NETPATH
NetPath_5
ID pathway
REACTOME
REACT_21402
CDO in myogenesis pathway
REACT_111045
Developmental Biology pathway
REACT_21303
Myogenesis pathway
KEGG
INOH
PID NCI
betacatenin_nuc_pathway
Regulation of nuclear beta catenin signaling and target gene transcription
Cross-References
SwissProt P13349
TrEMBL
UniProt Splice Variant
Entrez Gene 4617
UniGene Hs.178023
RefSeq NM_005593
HUGO HGNC:7565
OMIM 159990
CCDS CCDS9020
HPRD
IMGT
EMBL BC069373 CH471054 U27313 X14894
GenPept AAA69824 AAH69373 CAA33025 EAW97368
RNA Seq Atlas 4617

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca