Version 5.4
Homo sapiens Gene: ABHD10
Summary
InnateDB Gene IDBG-49660.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ABHD10
Gene Name abhydrolase domain containing 10
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000144827
Encoded Proteins
IDBP-49662
abhydrolase domain containing 10
IDBP-485246
abhydrolase domain containing 10
IDBP-479315
abhydrolase domain containing 10
IDBP-475563
abhydrolase domain containing 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a mitochondrially-localized enzyme that acts in liver cells as a hydrolase. The encoded protein removes glucuronide from mycophenolic acid acyl-glucuronide. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:111979010-111993363
Strand Forward strand
Band q13.2
Transcripts
ENST00000273359 ENSP00000273359
ENST00000491580 ENSP00000418162
ENST00000497293
ENST00000493784 ENSP00000417880
ENST00000494817 ENSP00000418973
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0008236 serine-type peptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006508 proteolysis
GO:0008152 metabolic process
GO:0019391 glucuronoside catabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033157
View Gene Order
ENSBTAG00000004601
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.477115 Hs.743466
RefSeq NM_001272069 NM_018394
HUGO
OMIM
CCDS CCDS2963 CCDS63718
HPRD 07751
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca