Version 5.4
Homo sapiens Protein: ABHD10
Summary
InnateDB Protein IDBP-49662.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ABHD10
Protein Name abhydrolase domain containing 10
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000273359
InnateDB Gene IDBG-49660 (ABHD10)
Protein Structure
UniProt Annotation
Function Catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, a metabolite of the immunosuppressant drug mycophenolate. {ECO:0000269PubMed:22294686}.
Subcellular Localization Mitochondrion {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0008236 serine-type peptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006508 proteolysis
GO:0008152 metabolic process
GO:0019391 glucuronoside catabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000073 Alpha/beta hydrolase fold-1
IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00561
PF00326
PRINTS PR00111
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NUJ1
PhosphoSite PhosphoSite-Q9NUJ1
TrEMBL B7Z6A8
UniProt Splice Variant
Entrez Gene 55347
UniGene Hs.743466
RefSeq NP_060864
HUGO HGNC:25656
OMIM
CCDS CCDS2963
HPRD 07751
IMGT
EMBL AC060225 AK002204 AK300018 AL713726 BC014516 CH471052
GenPept AAH14516 BAA92133 BAH13194 CAD28516 EAW79688 EAW79689

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca