Version 5.4
Homo sapiens Gene: OTUD7A
Summary
InnateDB Gene IDBG-5011.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OTUD7A
Gene Name OTU domain containing 7A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000169918
Encoded Proteins
IDBP-5015
OTU domain containing 7A
IDBP-595247
OTU domain containing 7A
IDBP-592035
OTU domain containing 7A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. OTUD7A belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.[supplied by OMIM, May 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:31475398-31870789
Strand Reverse strand
Band q13.3
Transcripts
ENST00000307050 ENSP00000305926
ENST00000560536 ENSP00000453622
ENST00000558371
ENST00000560598 ENSP00000453883
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0004843 ubiquitin-specific protease activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0035871 protein K11-linked deubiquitination
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033510
View Gene Order
ENSBTAG00000006868
Not yet available
Cross-References
SwissProt Q8TE49
TrEMBL H0YMI7 H0YN66
UniProt Splice Variant
Entrez Gene 161725
UniGene
RefSeq NM_130901 XM_006720413
HUGO HGNC:20718
OMIM 612024
CCDS CCDS10026
HPRD
IMGT
EMBL AC021316 AC026951 AC079969 AC104266 AC104759 AJ430383 BC035668
GenPept AAH35668 CAD23047
RNA Seq Atlas 161725

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca