Version 5.4
Homo sapiens Gene: TIMM50
Summary
InnateDB Gene IDBG-50563.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TIMM50
Gene Name translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000105197
Encoded Proteins
IDBP-50565
translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
IDBP-602269
translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
IDBP-764991
IDBP-764251
IDBP-761372
IDBP-759971
IDBP-760818
IDBP-765658
IDBP-765152
IDBP-765799
IDBP-766270
IDBP-760432
IDBP-810952
translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:39480412-39493785
Strand Forward strand
Band q13.2
Transcripts
ENST00000314349 ENSP00000318115
ENST00000544017 ENSP00000445806
ENST00000595527
ENST00000595961
ENST00000598125
ENST00000601403 ENSP00000472184
ENST00000600878
ENST00000602028 ENSP00000470896
ENST00000597552
ENST00000594583 ENSP00000470994
ENST00000599733 ENSP00000472904
ENST00000595286
ENST00000601358 ENSP00000472476
ENST00000596239
ENST00000599794 ENSP00000472524
ENST00000601252 ENSP00000471142
ENST00000597782 ENSP00000469052
ENST00000597666 ENSP00000472723
ENST00000602265 ENSP00000472920
ENST00000607714 ENSP00000475531
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 53 experimentally validated interaction(s) in this database.
Experimentally validated
Total 53 [view]
Protein-Protein 53 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0004721 phosphoprotein phosphatase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0005134 interleukin-2 receptor binding
GO:0005515 protein binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0001836 release of cytochrome c from mitochondria
GO:0006470 protein dephosphorylation
GO:0006626 protein targeting to mitochondrion
GO:0007006 mitochondrial membrane organization
GO:0015031 protein transport
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005744 mitochondrial inner membrane presequence translocase complex
GO:0016021 integral component of membrane
GO:0016607 nuclear speck
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000003438
View Gene Order
ENSBTAG00000010480
Not yet available
Pathways
NETPATH
REACTOME
REACT_118595
Mitochondrial protein import pathway
REACT_17015
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.590956 Hs.597106 Hs.742476
RefSeq NM_001001563
HUGO
OMIM
CCDS CCDS33023
HPRD 12118
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca