Version 5.4
Homo sapiens Gene: RBM17
Summary
InnateDB Gene IDBG-50666.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RBM17
Gene Name RNA binding motif protein 17
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000134453
Encoded Proteins
IDBP-50668
RNA binding motif protein 17
IDBP-364215
RNA binding motif protein 17
IDBP-364217
RNA binding motif protein 17
IDBP-364218
RNA binding motif protein 17
IDBP-364220
RNA binding motif protein 17
IDBP-364223
RNA binding motif protein 17
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 9 and 15. [provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:6088987-6117457
Strand Forward strand
Band p15.1
Transcripts
ENST00000379888 ENSP00000369218
ENST00000437845 ENSP00000395448
ENST00000432931 ENSP00000408214
ENST00000446108 ENSP00000388638
ENST00000418631 ENSP00000402303
ENST00000447032 ENSP00000406024
ENST00000467214
ENST00000481147
ENST00000476706
ENST00000465906
ENST00000467080
ENST00000496762
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 36 [view]
Protein-Protein 35 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000380 alternative mRNA splicing, via spliceosome
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037197
View Gene Order
ENSBTAG00000021951
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa03040
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.603302 Hs.620308
RefSeq NM_001145547 NM_032905
HUGO
OMIM
CCDS CCDS7077
HPRD 09501
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca