Version 5.4
Homo sapiens Gene: TTC7A
Summary
InnateDB Gene IDBG-50690.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TTC7A
Gene Name tetratricopeptide repeat domain 7A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000068724
Encoded Proteins
IDBP-50692
tetratricopeptide repeat domain 7A
IDBP-240737
tetratricopeptide repeat domain 7A
IDBP-293540
tetratricopeptide repeat domain 7A
IDBP-293545
tetratricopeptide repeat domain 7A
IDBP-374740
tetratricopeptide repeat domain 7A
IDBP-374745
tetratricopeptide repeat domain 7A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The tetratricopeptide repeat (TPR) domain is defined by a degenerate consensus sequence of 34 amino acids. TPR domain-containing proteins, such as TTC7A, have diverse functions in cell cycle control, protein transport, phosphate turnover, and protein trafficking or secretion, and they can act as chaperones or scaffolding proteins (White et al., 2005 [PubMed 15718100]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:46916157-47076137
Strand Forward strand
Band p21
Transcripts
ENST00000319190 ENSP00000316699
ENST00000394850 ENSP00000378320
ENST00000409245 ENSP00000386307
ENST00000409825 ENSP00000386521
ENST00000441914 ENSP00000393022
ENST00000440051 ENSP00000401467
ENST00000461601
ENST00000474321
ENST00000491786
ENST00000484061
ENST00000484337
ENST00000496991
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006879 cellular iron ion homeostasis
GO:0030097 hemopoiesis
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036918
View Gene Order
ENSBTAG00000032558
Not yet available
Cross-References
SwissProt
TrEMBL F5H4E1 G5E9G4
UniProt Splice Variant
Entrez Gene 57217
UniGene Hs.370603 Hs.623671 Hs.736871
RefSeq NM_001288953 NM_001288951 NM_001288955 NM_020458 XM_005264439 XM_005264440
HUGO HGNC:19750
OMIM 609332
CCDS CCDS74510 CCDS33193 CCDS74511
HPRD 18239
IMGT
EMBL AC016722 AC073283 AC093732 CH471053
GenPept EAX00226
RNA Seq Atlas 57217

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca