Version 5.4
Homo sapiens Gene: ATP11A
Summary
InnateDB Gene IDBG-51817.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ATP11A
Gene Name ATPase, class VI, type 11A
Synonyms ATPIH; ATPIS
Species Homo sapiens
Ensembl Gene ENSG00000068650
Encoded Proteins
IDBP-51819
ATPase, class VI, type 11A
IDBP-51821
ATPase, class VI, type 11A
IDBP-373929
ATPase, class VI, type 11A
IDBP-373931
ATPase, class VI, type 11A
IDBP-373933
ATPase, class VI, type 11A
IDBP-484533
ATPase, class VI, type 11A
IDBP-478907
ATPase, class VI, type 11A
IDBP-806896
ATPase, class VI, type 11A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is an integral membrane ATPase. The encoded protein is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium across membranes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:112690329-112887168
Strand Forward strand
Band q34
Transcripts
ENST00000375645 ENSP00000364796
ENST00000375630 ENSP00000364781
ENST00000418678 ENSP00000396374
ENST00000419631 ENSP00000410824
ENST00000415301 ENSP00000402575
ENST00000459011
ENST00000487903 ENSP00000420387
ENST00000466946
ENST00000459908
ENST00000489577
ENST00000471555 ENSP00000420696
ENST00000495930
ENST00000493489
ENST00000479193
ENST00000610419 ENSP00000479392
ENST00000614170
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0004012 phospholipid-translocating ATPase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0019829 cation-transporting ATPase activity
GO:0046872 metal ion binding
Biological Process
GO:0006812 cation transport
GO:0008152 metabolic process
GO:0015914 phospholipid transport
GO:0045332 phospholipid translocation
Cellular Component
GO:0005765 lysosomal membrane
GO:0005769 early endosome
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0055037 recycling endosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031441
View Gene Order
ENSBTAG00000000446
Not yet available
Pathways
NETPATH
REACTOME
REACT_25149
Ion transport by P-type ATPases pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.29189 Hs.713345
RefSeq NM_015205 NM_032189 XM_005268299 XM_005268305 XM_005268306 XM_006719965
HUGO
OMIM
CCDS CCDS32011
HPRD 12059
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca