InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Atp11a

Summary

InnateDB Gene

IDBG-133518.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Atp11a

Gene Name

ATPase, class VI, type 11A

Synonyms

4930558F19Rik; Atpc1h; AU040868; Ih

Species

Mus musculus

Ensembl Gene

ENSMUSG00000031441

Encoded Proteins

IDBP-133520

ATPase, class VI, type 11A

IDBP-133522

ATPase, class VI, type 11A

IDBP-542097

ATPase, class VI, type 11A

IDBP-540259

ATPase, class VI, type 11A

IDBP-541856

ATPase, class VI, type 11A

IDBP-533963

ATPase, class VI, type 11A

IDBP-536560

ATPase, class VI, type 11A

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000068650:
The protein encoded by this gene is an integral membrane ATPase. The encoded protein is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium across membranes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:12757014-12868728

Strand

Forward strand

Band

A1.1

Transcripts

ENSMUST00000033818	ENSMUSP00000033818
ENSMUST00000091237	ENSMUSP00000088779
ENSMUST00000133338	ENSMUSP00000120625
ENSMUST00000125031
ENSMUST00000127197
ENSMUST00000132974	ENSMUSP00000117091
ENSMUST00000152273	ENSMUSP00000121989
ENSMUST00000136918
ENSMUST00000143359	ENSMUSP00000114312
ENSMUST00000131804	ENSMUSP00000121567
ENSMUST00000139545

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0000287	magnesium ion binding
GO:0004012	phospholipid-translocating ATPase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0019829	cation-transporting ATPase activity
GO:0046872	metal ion binding

Biological Process

GO:0006812	cation transport
GO:0008152	metabolic process
GO:0015914	phospholipid transport
GO:0045332	phospholipid translocation

Cellular Component

GO:0005765	lysosomal membrane
GO:0005769	early endosome
GO:0005783	endoplasmic reticulum
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0055037	recycling endosome

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000068650

View Gene Order

ENSBTAG00000000446

Not yet available

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_25149

Ion transport by P-type ATPases pathway

REACT_15518

Transmembrane transport of small molecules pathway

REACT_25300

Ion channel transport pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.257837 Mm.397747 Mm.462267 Mm.473870

RefSeq

NM_015804 XM_006508835 XM_006508836 XM_006508838 XM_006508839 XM_006508840

OMIM

CCDS

CCDS40223

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas