Version 5.4
Homo sapiens Gene: GTF2E1
Summary
InnateDB Gene IDBG-51929.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GTF2E1
Gene Name general transcription factor IIE, polypeptide 1, alpha 56kDa
Synonyms FE; TF2E1; TFIIE-A
Species Homo sapiens
Ensembl Gene ENSG00000153767
Encoded Proteins
IDBP-51931
general transcription factor IIE, polypeptide 1, alpha 56kDa
IDBP-483256
general transcription factor IIE, polypeptide 1, alpha 56kDa
IDBP-482103
general transcription factor IIE, polypeptide 1, alpha 56kDa
IDBP-483542
general transcription factor IIE, polypeptide 1, alpha 56kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:120742637-120783069
Strand Forward strand
Band q13.33
Transcripts
ENST00000283875 ENSP00000283875
ENST00000484715 ENSP00000417342
ENST00000469772 ENSP00000418808
ENST00000492959 ENSP00000417077
ENST00000497393
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 63 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 63 [view]
Protein-Protein 59 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0010467 gene expression
GO:0016032 viral process
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0045111 intermediate filament cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022828
View Gene Order
ENSBTAG00000016848
Not yet available
Pathways
NETPATH
REACTOME
REACT_1655
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
REACT_22107
RNA Polymerase II Pre-transcription Events pathway
REACT_2089
RNA Polymerase II Promoter Escape pathway
REACT_1851
RNA Polymerase II Transcription Initiation pathway
REACT_834
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
REACT_6332
HIV Transcription Initiation pathway
REACT_6253
RNA Polymerase II HIV Promoter Escape pathway
REACT_6233
Transcription of the HIV genome pathway
REACT_6361
Late Phase of HIV Life Cycle pathway
REACT_1366
RNA Polymerase II Transcription pathway
REACT_6256
HIV Life Cycle pathway
REACT_6185
HIV Infection pathway
REACT_71
Gene Expression pathway
REACT_116125
Disease pathway
KEGG
hsa03022
Basal transcription factors pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL C9IYL4
UniProt Splice Variant
Entrez Gene 2960
UniGene Hs.445272
RefSeq NM_005513
HUGO HGNC:4650
OMIM 189962
CCDS CCDS3002
HPRD 01799
IMGT
EMBL AC117472
GenPept
RNA Seq Atlas 2960

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca