Version 5.4
Homo sapiens Gene: VAT1
Summary
InnateDB Gene IDBG-52100.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VAT1
Gene Name vesicle amine transport protein 1 homolog (T. californica)
Synonyms VATI
Species Homo sapiens
Ensembl Gene ENSG00000108828
Encoded Proteins
IDBP-52102
vesicle amine transport protein 1 homolog (T. californica)
IDBP-386027
vesicle amine transport protein 1 homolog (T. californica)
IDBP-763993
IDBP-762169
IDBP-761614
IDBP-758120
IDBP-763606
IDBP-763478
IDBP-760198
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Synaptic vesicles are responsible for regulating the storage and release of neurotransmitters in the nerve terminal. The protein encoded by this gene is an abundant integral membrane protein of cholinergic synaptic vesicles and is thought to be involved in vesicular transport. It belongs to the quinone oxidoreductase subfamily of zinc-containing alcohol dehydrogenase proteins. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:43014605-43025123
Strand Reverse strand
Band q21.31
Transcripts
ENST00000355653 ENSP00000347872
ENST00000420567 ENSP00000408553
ENST00000589709 ENSP00000467131
ENST00000589828 ENSP00000468146
ENST00000592388 ENSP00000465239
ENST00000587173 ENSP00000465946
ENST00000587062 ENSP00000468401
ENST00000590924 ENSP00000466322
ENST00000587147 ENSP00000468621
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
Biological Process
GO:0010637 negative regulation of mitochondrial fusion
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005741 mitochondrial outer membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034993
View Gene Order
ENSBTAG00000007390
Not yet available
Cross-References
SwissProt
TrEMBL B0AZP7 B4DPX4 K7ENX2 K7ER81
UniProt Splice Variant
Entrez Gene 10493
UniGene Hs.514199
RefSeq NM_006373
HUGO HGNC:16919
OMIM 604631
CCDS CCDS11451
HPRD 05220
IMGT
EMBL AC055866 AC135721 AK298536 AK315838
GenPept BAF98729 BAG60736
RNA Seq Atlas 10493

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca