Version 5.4
Mus musculus Gene: Vat1
Summary
InnateDB Gene IDBG-212201.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vat1
Gene Name vesicle amine transport protein 1 homolog (T californica)
Synonyms VAT-1
Species Mus musculus
Ensembl Gene ENSMUSG00000034993
Encoded Proteins
IDBP-212203
vesicle amine transport protein 1 homolog (T californica)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108828:
Synaptic vesicles are responsible for regulating the storage and release of neurotransmitters in the nerve terminal. The protein encoded by this gene is an abundant integral membrane protein of cholinergic synaptic vesicles and is thought to be involved in vesicular transport. It belongs to the quinone oxidoreductase subfamily of zinc-containing alcohol dehydrogenase proteins. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:101458745-101466230
Strand Reverse strand
Band D
Transcripts
ENSMUST00000040430 ENSMUSP00000048350
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
Biological Process
GO:0010637 negative regulation of mitochondrial fusion
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005741 mitochondrial outer membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000108828
View Gene Order
ENSBTAG00000007390
Not yet available
Cross-References
SwissProt Q62465
TrEMBL Q499X4 Q5RKP0
UniProt Splice Variant
Entrez Gene 26949
UniGene Mm.29210 Mm.401503
RefSeq NM_012037
OMIM
CCDS CCDS25472
HPRD
IMGT
MGI ID MGI:1349450
MGI Symbol Vat1
EMBL AK034795 AK145193 AK159310 AK160891 AK170371 BC024586 BC025496 BC085504 BC099678 CH466558 X95562
GenPept AAH24586 AAH25496 AAH85504 AAH99678 BAC28833 BAE26285 BAE34978 BAE36072 BAE41752 CAA64807 EDL34049
RNA Seq Atlas 26949

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca