Version 5.4
Homo sapiens Gene: EAF2
Summary
InnateDB Gene IDBG-52225.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EAF2
Gene Name ELL associated factor 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000145088
Encoded Proteins
IDBP-52227
ELL associated factor 2
IDBP-382989
ELL associated factor 2
IDBP-478842
ELL associated factor 2
IDBP-485284
ELL associated factor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:121835183-121886526
Strand Forward strand
Band q13.33
Transcripts
ENST00000273668 ENSP00000273668
ENST00000451944 ENSP00000410708
ENST00000490434 ENSP00000418374
ENST00000465664
ENST00000490477 ENSP00000419552
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228 RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006915 apoptotic process
GO:0030308 negative regulation of cell growth
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development
Cellular Component
GO:0005654 nucleoplasm
GO:0016607 nuclear speck
GO:0032783 ELL-EAF complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022838
View Gene Order
ENSBTAG00000013070
Not yet available
Cross-References
SwissProt Q96CJ1
TrEMBL B4DWJ3 F8WCI9 F8WF04
UniProt Splice Variant
Entrez Gene 55840
UniGene Hs.732120
RefSeq NM_018456 XM_005247620
HUGO HGNC:23115
OMIM 607659
CCDS CCDS3006
HPRD
IMGT
EMBL AC072031 AC119736 AF217516 AF517829 AK301560 AY049020 BC014209
GenPept AAF67627 AAH14209 AAL12223 AAO63811 BAG63055
RNA Seq Atlas 55840

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca