Version 5.4
Homo sapiens Gene: SPINK6
Summary
InnateDB Gene IDBG-52421.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPINK6
Gene Name serine peptidase inhibitor, Kazal type 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000178172
Encoded Proteins
IDBP-52423
serine peptidase inhibitor, Kazal type 6
IDBP-479165
serine peptidase inhibitor, Kazal type 6
IDBP-811516
serine peptidase inhibitor, Kazal type 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a Kazal-type serine protease inhibitor that acts on kallikrein-related peptidases in the skin. Two transcript variants the same protein have been found for this gene. [provided by RefSeq, Aug 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:148202794-148215137
Strand Forward strand
Band q32
Transcripts
ENST00000325630 ENSP00000324870
ENST00000514389 ENSP00000421119
ENST00000621437 ENSP00000481309
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005515 protein binding
Biological Process
GO:0010951 negative regulation of endopeptidase activity
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000055095
View Gene Order
ENSBTAG00000033470
Not yet available
Cross-References
SwissProt
TrEMBL D6RGX9
UniProt Splice Variant
Entrez Gene 404203
UniGene
RefSeq NM_001195290 NM_205841
HUGO HGNC:29486
OMIM 615868
CCDS CCDS34268
HPRD
IMGT
EMBL AC011346 AY358716 BC032003 CH471062 GQ504704 GQ504705
GenPept AAH32003 AAQ89078 ADM46526 ADM46527 EAW61813
RNA Seq Atlas 404203

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca