Version 5.4
Homo sapiens Gene: LGALS12
Summary
InnateDB Gene IDBG-52486.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LGALS12
Gene Name lectin, galactoside-binding, soluble, 12
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000133317
Encoded Proteins
IDBP-52488
lectin, galactoside-binding, soluble, 12
IDBP-52490
lectin, galactoside-binding, soluble, 12
IDBP-241219
lectin, galactoside-binding, soluble, 12
IDBP-376722
lectin, galactoside-binding, soluble, 12
IDBP-376723
lectin, galactoside-binding, soluble, 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the galectin superfamily, a group of beta-galactoside-binding proteins with conserved carbohydrate recognition domains. The related mouse protein is a primary regulator of the early stages of adipose tissue development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:63506084-63516774
Strand Forward strand
Band q12.3
Transcripts
ENST00000255684 ENSP00000255684
ENST00000340246 ENSP00000339374
ENST00000394618 ENSP00000378116
ENST00000415491 ENSP00000394659
ENST00000425950 ENSP00000399093
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0030246 carbohydrate binding
GO:0030395 lactose binding
Biological Process
GO:0097193 intrinsic apoptotic signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024972
View Gene Order
ENSBTAG00000007108
Not yet available
Cross-References
SwissProt Q96DT0
TrEMBL
UniProt Splice Variant
Entrez Gene 85329
UniGene Hs.502774
RefSeq NM_033101 NM_001142535 NM_001142536 NM_001142537 NM_001142538
HUGO HGNC:15788
OMIM 606096
CCDS CCDS8045 CCDS44633 CCDS44634 CCDS44635 CCDS53648
HPRD 16196
IMGT
EMBL AF222695 AF244974 AF244975 AF244976 AF244977 AF310686 AF310687 AK313851 BC028222 CH471076
GenPept AAF34677 AAG40863 AAG40864 AAH28222 AAK77328 AAK77329 AAK77330 AAK77331 BAG36579 EAW74155
RNA Seq Atlas 85329

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca