Version 5.4
Homo sapiens Protein: LGALS12
Summary
InnateDB Protein IDBP-376722.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LGALS12
Protein Name lectin, galactoside-binding, soluble, 12
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000394659
InnateDB Gene IDBG-52486 (LGALS12)
Protein Structure
UniProt Annotation
Function Binds lactose. May participate in the apoptosis of adipocytes.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity Not widely expressed. Predominantly expressed in adipose tissue.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0030246 carbohydrate binding
GO:0030395 lactose binding
Biological Process
GO:0097193 intrinsic apoptotic signaling pathway
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001079 Galectin, carbohydrate recognition domain
IPR008985 Concanavalin A-like lectin/glucanases superfamily
PFAM PF00337
PRINTS
PIRSF
SMART SM00276
SM00908
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96DT0
PhosphoSite PhosphoSite-Q96DT0
TrEMBL
UniProt Splice Variant
Entrez Gene 85329
UniGene Hs.502774
RefSeq NP_001136009
HUGO HGNC:15788
OMIM 606096
CCDS CCDS44634
HPRD 16196
IMGT
EMBL AF222695 AF244974 AF244975 AF244976 AF244977 AF310686 AF310687 AK313851 BC028222 CH471076
GenPept AAF34677 AAG40863 AAG40864 AAH28222 AAK77328 AAK77329 AAK77330 AAK77331 BAG36579 EAW74155

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca