InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: CYP2A13

Summary

InnateDB Gene

IDBG-52505.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CYP2A13

Gene Name

cytochrome P450, family 2, subfamily A, polypeptide 13

Synonyms

CPAD; CYP2A; CYPIIA13

Species

Homo sapiens

Ensembl Gene

ENSG00000197838

Encoded Proteins

IDBP-52507

cytochrome P450, family 2, subfamily A, polypeptide 13

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. Although its endogenous substrate has not been determined, it is known to metabolize 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a major nitrosamine specific to tobacco. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:41088472-41096195

Strand

Forward strand

Band

q13.2

Transcripts

ENST00000330436

ENSP00000332679

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005506	iron ion binding
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037	heme binding
GO:0070330	aromatase activity