Version 5.4
Homo sapiens Gene: MEOX1
Summary
InnateDB Gene IDBG-52858.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MEOX1
Gene Name mesenchyme homeobox 1
Synonyms KFS2; MOX1
Species Homo sapiens
Ensembl Gene ENSG00000005102
Encoded Proteins
IDBP-52860
mesenchyme homeobox 1
IDBP-52862
mesenchyme homeobox 1
IDBP-243167
mesenchyme homeobox 1
IDBP-599517
mesenchyme homeobox 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the molecular signaling network regulating somite development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:43640388-43661954
Strand Reverse strand
Band q21.31
Transcripts
ENST00000318579 ENSP00000321684
ENST00000329168 ENSP00000328678
ENST00000393661 ENSP00000377271
ENST00000549132 ENSP00000449049
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 9 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0071837 HMG box domain binding
Biological Process
GO:0001757 somite specification
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
GO:0008150 biological_process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000001493
View Gene Order
ENSBTAG00000015751
Not yet available
Cross-References
SwissProt
TrEMBL F8VXS6
UniProt Splice Variant
Entrez Gene 4222
UniGene Hs.438
RefSeq NM_001040002 NM_004527 NM_013999
HUGO HGNC:7013
OMIM 600147
CCDS CCDS11466 CCDS11467 CCDS42343
HPRD 02537
IMGT
EMBL AC004149 AC068675
GenPept
RNA Seq Atlas 4222

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca