Version 5.4
Homo sapiens Gene: CEACAM5
Summary
InnateDB Gene IDBG-53174.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CEACAM5
Gene Name carcinoembryonic antigen-related cell adhesion molecule 5
Synonyms CD66e; CEA
Species Homo sapiens
Ensembl Gene ENSG00000105388
Encoded Proteins
IDBP-53176
carcinoembryonic antigen-related cell adhesion molecule 5
IDBP-232713
carcinoembryonic antigen-related cell adhesion molecule 5
IDBP-294668
carcinoembryonic antigen-related cell adhesion molecule 5
IDBP-762696
IDBP-759759
IDBP-809807
carcinoembryonic antigen-related cell adhesion molecule 5
IDBP-809809
carcinoembryonic antigen-related cell adhesion molecule 5
IDBP-809814
carcinoembryonic antigen-related cell adhesion molecule 5
IDBP-809817
carcinoembryonic antigen-related cell adhesion molecule 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of the CEACAM subfamily, including CEACAM5, belong to the CEA gene family. For general information on the CEA gene family, see CEACAM1 (MIM 109770).[supplied by OMIM, Oct 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:41576273-41729798
Strand Forward strand
Band q13.2
Transcripts
ENST00000221992 ENSP00000221992
ENST00000398599 ENSP00000381600
ENST00000405816 ENSP00000385072
ENST00000460121
ENST00000595403 ENSP00000468997
ENST00000596606
ENST00000595113 ENSP00000473252
ENST00000617332 ENSP00000482303
ENST00000615021 ENSP00000482157
ENST00000621956 ENSP00000483025
ENST00000616453 ENSP00000480800
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 7 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0034235 GPI anchor binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0010832 negative regulation of myotube differentiation
GO:0034109 homotypic cell-cell adhesion
GO:0043066 negative regulation of apoptotic process
GO:2000811 negative regulation of anoikis
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016323 basolateral plasma membrane
GO:0031225 anchored component of membrane
GO:0070062 extracellular vesicular exosome
GO:0071575 integral component of external side of plasma membrane
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 1048
UniGene Hs.709196
RefSeq NM_001291484 NM_004363 XM_005258413
HUGO HGNC:1817
OMIM 114890
CCDS CCDS12584
HPRD 00274
IMGT
EMBL
GenPept
RNA Seq Atlas 1048

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca