Version 5.4
Homo sapiens Gene: PYY
Summary
InnateDB Gene IDBG-53192.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PYY
Gene Name peptide YY
Synonyms PYY-I; PYY1
Species Homo sapiens
Ensembl Gene ENSG00000131096
Encoded Proteins
IDBP-53194
peptide YY
IDBP-763739
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is proteolytically processed to release a peptide that inhibits pancreatic secretion and mobility in the gut. Rare variations in this gene could increase susceptibility to obesity. [provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:43952738-44004469
Strand Reverse strand
Band q21.31
Transcripts
ENST00000360085 ENSP00000353198
ENST00000592796 ENSP00000467310
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
GO:0005184 neuropeptide hormone activity
GO:0005515 protein binding
Biological Process
GO:0006928 cellular component movement
GO:0007010 cytoskeleton organization
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007267 cell-cell signaling
GO:0007586 digestion
GO:0007631 feeding behavior
GO:0008283 cell proliferation
GO:0042755 eating behavior
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000017311
View Gene Order
ENSBTAG00000046022
Not yet available
Pathways
NETPATH
REACTOME
REACT_19231
G alpha (i) signalling events pathway
REACT_14819
Peptide ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
INOH
INOH website
GPCR signaling pathway
PID NCI
Cross-References
SwissProt P10082
TrEMBL
UniProt Splice Variant
Entrez Gene 5697
UniGene
RefSeq NM_004160
HUGO HGNC:9748
OMIM 600781
CCDS CCDS32662
HPRD 02869
IMGT
EMBL AC007993 BC041057 CR542129 D13897 D13899 D13902 L25648
GenPept AAA36433 AAH41057 BAA02997 BAA02998 BAA03000 BAA03002 CAG46926
RNA Seq Atlas 5697

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca