Homo sapiens Gene: SLC22A11
Summary
InnateDB Gene IDBG-53978.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC22A11
Gene Name solute carrier family 22 (organic anion/urate transporter), member 11
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000168065
Encoded Proteins
solute carrier family 22 (organic anion/urate transporter), member 11
solute carrier family 22 (organic anion/urate transporter), member 11
solute carrier family 22 (organic anion/urate transporter), member 11
solute carrier family 22 (organic anion/urate transporter), member 11
solute carrier family 22 (organic anion/urate transporter), member 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and is found mainly in the kidney and in the placenta, where it may act to prevent potentially harmful organic anions from reaching the fetus. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:64555626-64572875
Strand Forward strand
Band q13.1
Transcripts
ENST00000301891 ENSP00000301891
ENST00000377585 ENSP00000366809
ENST00000377581 ENSP00000366804
ENST00000428570 ENSP00000394043
ENST00000416590 ENSP00000413508
ENST00000478051
ENST00000490834
ENST00000460745
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005452 inorganic anion exchanger activity
GO:0005515 protein binding
GO:0008514 organic anion transmembrane transporter activity
GO:0015347 sodium-independent organic anion transmembrane transporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0015711 organic anion transport
GO:0046415 urate metabolic process
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Organic anion transport pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Transmembrane transport of small molecules pathway
Organic cation/anion/zwitterion transport pathway
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9NSA0
TrEMBL
UniProt Splice Variant
Entrez Gene 55867
UniGene Hs.220844 Hs.657603
RefSeq NM_018484
HUGO HGNC:18120
OMIM 607097
CCDS CCDS8074
HPRD 06161
IMGT
EMBL AB026116 AC044790 AK075224 AK129930 AK222869 AK290791 BC034384 CH471076
GenPept AAH34384 AAK68155 BAA95316 BAC11483 BAC85252 BAD96589 BAF83480 EAW74269
RNA Seq Atlas 55867