Version 5.4
Homo sapiens Gene: APOPT1
Summary
InnateDB Gene IDBG-547131.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APOPT1
Gene Name apoptogenic 1, mitochondrial
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000256053
Encoded Proteins
IDBP-295306
apoptogenic 1
IDBP-378142
apoptogenic 1
IDBP-378144
apoptogenic 1
IDBP-590572
apoptogenic 1
IDBP-586931
apoptogenic 1
IDBP-585342
apoptogenic 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 14:103562962-103607523
Strand Forward strand
Band q32.33
Transcripts
ENST00000409074 ENSP00000386485
ENST00000440963 ENSP00000388067
ENST00000458117 ENSP00000408525
ENST00000489117 ENSP00000451788
ENST00000495778 ENSP00000451703
ENST00000492189
ENST00000477116
ENST00000473127
ENST00000497901
ENST00000476323
ENST00000474271
ENST00000555660 ENSP00000450756
ENST00000557079
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0034393 positive regulation of smooth muscle cell apoptotic process
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0090200 positive regulation of release of cytochrome c from mitochondria
GO:0097193 intrinsic apoptotic signaling pathway
Cellular Component
GO:0005739 mitochondrion
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037787
View Gene Order
ENSBTAG00000021199
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.598441 Hs.610578
RefSeq NM_032374
HUGO
OMIM
CCDS CCDS9983
HPRD 12637
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca