Version 5.4
| Homo sapiens Gene: SLC5A8 | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-547244.3 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | SLC5A8 | ||||||||||
| Gene Name | solute carrier family 5 (iodide transporter), member 8 | ||||||||||
| Synonyms | |||||||||||
| Species | Homo sapiens | ||||||||||
| Ensembl Gene | ENSG00000256870 | ||||||||||
| Encoded Proteins |
solute carrier family 5 (iodide transporter), member 8
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
SLC5A8 has been shown to transport iodide by a passive mechanism (Rodriguez et al., 2002 [PubMed 12107270]) and monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism (Gopal et al., 2004 [PubMed 15322102]). In kidney, SLC5A8 functions as a high-affinity sodium-coupled lactate transporter involved in reabsorption of lactate and maintenance of blood lactate levels (Thangaraju et al., 2006 [PubMed 16873376]).[supplied by OMIM, Dec 2008] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 12:101155493-101210407 | ||||||||||
| Strand | Reverse strand | ||||||||||
| Band | q23.2 | ||||||||||
| Transcripts |
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| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Organic anion transporters pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
Transmembrane transport of small molecules pathway
SLC-mediated transmembrane transport pathway
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| KEGG | |||||||||||
| INOH | |||||||||||
| PID NCI | |||||||||||
| Cross-References | |||||||||||
| SwissProt | Q8N695 | ||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | 160728 | ||||||||||
| UniGene | Hs.444536 | ||||||||||
| RefSeq | NM_145913 | ||||||||||
| HUGO | HGNC:19119 | ||||||||||
| OMIM | 608044 | ||||||||||
| CCDS | CCDS9080 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | AC079953 AF536216 AF536217 AY081220 BC110492 CH471054 | ||||||||||
| GenPept | AAI10493 AAL88746 AAP46193 AAP46194 EAW97649 | ||||||||||
| RNA Seq Atlas | 160728 | ||||||||||