Homo sapiens Gene: PIGY
Summary
InnateDB Gene IDBG-547415.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIGY
Gene Name phosphatidylinositol glycan anchor biosynthesis, class Y
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000255072
Encoded Proteins
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is part of the GPI-N-acetylglucosaminyltransferase (GIP-GnT) complex which initiates the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is synthesized in the endoplasmic reticulum and serves as an anchor for many surface proteins. Proteins containing GPI anchors can have an important role in cell-cell interactions. The transcript for this gene is bicistronic. The downstream open reading frame encodes this GPI-GnT complex protein, while the upstream open reading frame encodes a protein with unknown function, as represented by GeneID:100996939. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:88521573-88521789
Strand Reverse strand
Band q22.1
Transcripts
ENST00000527353 ENSP00000432688
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006506 GPI anchor biosynthetic process
Cellular Component
GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q3MUY2
TrEMBL
UniProt Splice Variant
Entrez Gene 84992
UniGene
RefSeq NM_001042616
HUGO HGNC:28213
OMIM 610662
CCDS CCDS54778
HPRD 17492
IMGT
EMBL AB206972 BC007876
GenPept AAH07876 BAE44507
RNA Seq Atlas 84992