Version 5.4
Homo sapiens Protein: PIGY
Summary
InnateDB Protein IDBP-592239.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIGY
Protein Name Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000432688
InnateDB Gene IDBG-547415 (PIGY)
Protein Structure
UniProt Annotation
Function Component of the GPI-GlcNAc transferase (GPI-GnT) complex in the endoplasmic reticulum, a complex that catalyzes transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI- anchors for cell surface proteins. May act by regulating the catalytic subunit PIGA. {ECO:0000269PubMed:16162815}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000269PubMed:16162815}; Multi-pass membrane protein {ECO:0000269PubMed:16162815}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006506 GPI anchor biosynthetic process
Cellular Component
GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3MUY2
PhosphoSite PhosphoSite-Q3MUY2
TrEMBL
UniProt Splice Variant
Entrez Gene 84992
UniGene
RefSeq NP_001036081
HUGO HGNC:28213
OMIM 610662
CCDS CCDS54778
HPRD 17492
IMGT
EMBL AB206972 BC007876
GenPept AAH07876 BAE44507

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca