Version 5.4
Homo sapiens Gene: RIC8B
Summary
InnateDB Gene IDBG-54957.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RIC8B
Gene Name resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000111785
Encoded Proteins
IDBP-54959
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
IDBP-244839
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
IDBP-244841
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
IDBP-595288
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
IDBP-586174
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
IDBP-592559
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
IDBP-602346
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
IDBP-597906
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
IDBP-599472
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
IDBP-716518
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:106774595-106889316
Strand Forward strand
Band q23.3
Transcripts
ENST00000355478 ENSP00000347662
ENST00000392839 ENSP00000376583
ENST00000392837 ENSP00000376582
ENST00000462949 ENSP00000435301
ENST00000470628
ENST00000470960 ENSP00000436359
ENST00000550215 ENSP00000447801
ENST00000548914 ENSP00000447701
ENST00000552619 ENSP00000448743
ENST00000549643 ENSP00000450396
ENST00000546449 ENSP00000464118
ENST00000551756
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001965 G-protein alpha-subunit binding
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005488 binding
Biological Process
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005938 cell cortex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000035620
View Gene Order
ENSBTAG00000000147
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.607848
RefSeq NM_018157 XM_005268998 XM_005268999
HUGO
OMIM
CCDS CCDS9109
HPRD 16452
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca