Version 5.4
Homo sapiens Gene: TAF1L
Summary
InnateDB Gene IDBG-56102.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAF1L
Gene Name TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000122728
Encoded Proteins
IDBP-484842
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus is intronless, and apparently arose in the primate lineage from retrotransposition of the transcript from the multi-exon TAF1 locus on the X chromosome. The gene is expressed in male germ cells, and the product has been shown to function interchangeably with the TAF1 product. [provided by RefSeq, Aug 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:32629454-32635669
Strand Reverse strand
Band p21.1
Transcripts
ENST00000242310 ENSP00000418379
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0004402 histone acetyltransferase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0017025 TBP-class protein binding
GO:0070577 lysine-acetylated histone binding
Biological Process
GO:0006352 DNA-templated transcription, initiation
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006468 protein phosphorylation
GO:0007140 male meiosis
GO:0016573 histone acetylation
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0005575 cellular_component
GO:0005669 transcription factor TFIID complex
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_1655
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening pathway
REACT_22107
RNA Polymerase II Pre-transcription Events pathway
REACT_2089
RNA Polymerase II Promoter Escape pathway
REACT_1851
RNA Polymerase II Transcription Initiation pathway
REACT_834
RNA Polymerase II Transcription Initiation And Promoter Clearance pathway
REACT_6332
HIV Transcription Initiation pathway
REACT_6253
RNA Polymerase II HIV Promoter Escape pathway
REACT_6233
Transcription of the HIV genome pathway
REACT_6361
Late Phase of HIV Life Cycle pathway
REACT_1366
RNA Polymerase II Transcription pathway
REACT_6256
HIV Life Cycle pathway
REACT_6185
HIV Infection pathway
REACT_71
Gene Expression pathway
REACT_116125
Disease pathway
KEGG
hsa03022
Basal transcription factors pathway
INOH
PID NCI
Cross-References
SwissProt Q8IZX4
TrEMBL
UniProt Splice Variant
Entrez Gene 6872
UniGene Hs.591086
RefSeq NM_153809 XM_006724681
HUGO HGNC:18056
OMIM 313650 607798
CCDS CCDS35003
HPRD
IMGT
EMBL AF390562
GenPept AAN40840
RNA Seq Atlas 138474 6872

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca