Version 5.4
Homo sapiens Gene: H1FOO
Summary
InnateDB Gene IDBG-56105.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol H1FOO
Gene Name H1 histone family, member O, oocyte-specific
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000178804
Encoded Proteins
IDBP-56107
H1 histone family, member O, oocyte-specific
IDBP-479230
H1 histone family, member O, oocyte-specific
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The protein encoded is a member of the histone H1 family. The related mouse gene is expressed only in oocytes. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:129543214-129551467
Strand Forward strand
Band q22.1
Transcripts
ENST00000324382 ENSP00000319799
ENST00000503977 ENSP00000422964
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0031492 nucleosomal DNA binding
Biological Process
GO:0006334 nucleosome assembly
GO:0007126 meiotic nuclear division
GO:0016584 nucleosome positioning
GO:0044030 regulation of DNA methylation
GO:2000737 negative regulation of stem cell differentiation
Cellular Component
GO:0000786 nucleosome
GO:0001674 female germ cell nucleus
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000042279
View Gene Order
ENSBTAG00000001812
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8IZA3
TrEMBL
UniProt Splice Variant
Entrez Gene 132243
UniGene Hs.97358
RefSeq XM_005247123 NM_153833
HUGO HGNC:18463
OMIM
CCDS CCDS3064
HPRD 13621
IMGT
EMBL AY158091 BC047943 CH471052
GenPept AAH47943 AAN46899 EAW79242 EAW79243
RNA Seq Atlas 132243

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca