Version 5.4
Homo sapiens Gene: FAM109A
Summary
InnateDB Gene IDBG-57442.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAM109A
Gene Name family with sequence similarity 109, member A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000198324
Encoded Proteins
IDBP-57444
family with sequence similarity 109, member A
IDBP-598764
family with sequence similarity 109, member A
IDBP-601766
family with sequence similarity 109, member A
IDBP-601411
family with sequence similarity 109, member A
IDBP-598876
family with sequence similarity 109, member A
IDBP-811135
family with sequence similarity 109, member A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that localizes to the endosome and interacts with the enzyme, inositol polyphosphate 5-phosphatase OCRL-1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:111360651-111369121
Strand Reverse strand
Band q24.12
Transcripts
ENST00000361483 ENSP00000354461
ENST00000547838 ENSP00000447353
ENST00000548163 ENSP00000449994
ENST00000547710 ENSP00000447349
ENST00000549321 ENSP00000447539
ENST00000624311 ENSP00000485417
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0001881 receptor recycling
GO:0007032 endosome organization
GO:0042147 retrograde transport, endosome to Golgi
Cellular Component
GO:0005769 early endosome
GO:0005802 trans-Golgi network
GO:0030136 clathrin-coated vesicle
GO:0055037 recycling endosome
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.173088
RefSeq NM_001177996 NM_001177997 NM_144671
HUGO
OMIM
CCDS CCDS53833 CCDS9152
HPRD 08127
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca