Homo sapiens Gene: CEP63
Summary
InnateDB Gene IDBG-57578.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CEP63
Gene Name centrosomal protein 63kDa
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000182923
Encoded Proteins
centrosomal protein 63kDa
centrosomal protein 63kDa
centrosomal protein 63kDa
centrosomal protein 63kDa
centrosomal protein 63kDa
centrosomal protein 63kDa
centrosomal protein 63kDa
centrosomal protein 63kDa
centrosomal protein 63kDa
centrosomal protein 63kDa
centrosomal protein 63kDa
centrosomal protein 63kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein with six coiled-coil domains. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. Several alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:134485743-134575017
Strand Forward strand
Band q22.2
Transcripts
ENST00000332047 ENSP00000328382
ENST00000354446 ENSP00000346432
ENST00000337090 ENSP00000336524
ENST00000383229 ENSP00000372716
ENST00000514412
ENST00000511574 ENSP00000424626
ENST00000504013
ENST00000512894 ENSP00000423225
ENST00000513612 ENSP00000426129
ENST00000508778 ENSP00000422685
ENST00000510625
ENST00000504929 ENSP00000426866
ENST00000514678 ENSP00000427526
ENST00000513295
ENST00000606977 ENSP00000475903
ENST00000620544 ENSP00000482219
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
Experimentally validated
Total 31 [view]
Protein-Protein 31 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000077 DNA damage checkpoint
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000278 mitotic cell cycle
GO:0007067 mitotic nuclear division
GO:0007099 centriole replication
GO:0042770 signal transduction in response to DNA damage
GO:0051225 spindle assembly
Cellular Component
GO:0000922 spindle pole
GO:0005813 centrosome
GO:0005814 centriole
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Regulation of PLK1 Activity at G2/M Transition pathway
Loss of Nlp from mitotic centrosomes pathway
Loss of proteins required for interphase microtubule organization� from the centrosome pathway
Recruitment of mitotic centrosome proteins and complexes pathway
Cell Cycle pathway
Centrosome maturation pathway
G2/M Transition pathway
Cell Cycle, Mitotic pathway
Mitotic G2-G2/M phases pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001042383 NM_001042384 NM_001042400 NM_025180 XM_005247795 XM_005247797 XM_005247799 XM_006713759 XM_006713760 XM_006713764 XM_006713766
HUGO
OMIM
CCDS CCDS3086 CCDS43152 CCDS43153 CCDS43154
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas