Version 5.4
Homo sapiens Gene: OVOL1
Summary
InnateDB Gene IDBG-57737.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OVOL1
Gene Name ovo-like 1(Drosophila)
Synonyms HOVO1
Species Homo sapiens
Ensembl Gene ENSG00000172818
Encoded Proteins
IDBP-57739
ovo-like 1(Drosophila)
IDBP-591324
ovo-like 1(Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a putative zinc finger containing transcription factor that is highly similar to homologous protein in Drosophila and mouse. Based on known functions in these species, this protein is likely involved in hair formation and spermatogenesis in human as well. [provided by RefSeq, Aug 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:65787022-65797219
Strand Forward strand
Band q13.1
Transcripts
ENST00000335987 ENSP00000337862
ENST00000531907
ENST00000532448 ENSP00000434220
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001078 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001822 kidney development
GO:0006366 transcription from RNA polymerase II promoter
GO:0007010 cytoskeleton organization
GO:0007283 spermatogenesis
GO:0007498 mesoderm development
GO:0008544 epidermis development
GO:0009913 epidermal cell differentiation
GO:0043588 skin development
GO:0051729 germline cell cycle switching, mitotic to meiotic cell cycle
GO:1901994 negative regulation of meiotic cell cycle phase transition
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024922
View Gene Order
ENSBTAG00000012656
Not yet available
Cross-References
SwissProt
TrEMBL G3V1B0
UniProt Splice Variant
Entrez Gene 5017
UniGene Hs.134434 Hs.692307
RefSeq NM_004561 XM_005274018
HUGO HGNC:8525
OMIM 602313
CCDS CCDS8112
HPRD 09080
IMGT
EMBL AP001266 CH471076
GenPept EAW74439
RNA Seq Atlas 5017

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca