Version 5.4
Homo sapiens Gene: STAG1
Summary
InnateDB Gene IDBG-57884.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STAG1
Gene Name stromal antigen 1
Synonyms SA1; SCC3A
Species Homo sapiens
Ensembl Gene ENSG00000118007
Encoded Proteins
IDBP-57886
stromal antigen 1
IDBP-57888
stromal antigen 1
IDBP-380467
stromal antigen 1
IDBP-483146
stromal antigen 1
IDBP-479242
stromal antigen 1
IDBP-479513
stromal antigen 1
IDBP-481881
stromal antigen 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:136336233-136752403
Strand Reverse strand
Band q22.3
Transcripts
ENST00000236698 ENSP00000236698
ENST00000383202 ENSP00000372689
ENST00000434713 ENSP00000404396
ENST00000483235 ENSP00000419093
ENST00000465961
ENST00000487065 ENSP00000418472
ENST00000492318 ENSP00000419317
ENST00000462818
ENST00000480733 ENSP00000420789
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 34 [view]
Protein-Protein 34 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0007059 chromosome segregation
GO:0007067 mitotic nuclear division
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol
GO:0030054 cell junction
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037286
View Gene Order
ENSBTAG00000035437
Not yet available
Pathways
NETPATH
REACTOME
REACT_75792
Meiotic synapsis pathway
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_150421
Cohesin Loading onto Chromatin pathway
REACT_1932
Mitotic Telophase/Cytokinesis pathway
REACT_150266
Establishment of Sister Chromatid Cohesion pathway
REACT_899
S Phase pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_1275
Mitotic Anaphase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_111183
Meiosis pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
KEGG
hsa04110
Cell cycle pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.412586
RefSeq NM_005862
HUGO
OMIM
CCDS CCDS3090
HPRD 05076
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca