Version 5.4
Homo sapiens Gene: REG3A
Summary
InnateDB Gene IDBG-58484.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol REG3A
Gene Name regenerating islet-derived 3 alpha
Synonyms HIP; HIP/PAP; INGAP; PAP; PAP-H; PAP1; PBCGF; REG-III; REG3
Species Homo sapiens
Ensembl Gene ENSG00000172016
Encoded Proteins
IDBP-58486
regenerating islet-derived 3 alpha
IDBP-242724
regenerating islet-derived 3 alpha
IDBP-295433
regenerating islet-derived 3 alpha
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this gene is observed during pancreatic inflammation and liver carcinogenesis. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:79157003-79159753
Strand Reverse strand
Band p12
Transcripts
ENST00000305165 ENSP00000304311
ENST00000393878 ENSP00000377456
ENST00000409839 ENSP00000386630
ENST00000490901
ENST00000464746
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0030246 carbohydrate binding
Biological Process
GO:0006953 acute-phase response
GO:0007157 heterophilic cell-cell adhesion
GO:0007275 multicellular organismal development
GO:0008283 cell proliferation
GO:0010838 positive regulation of keratinocyte proliferation
GO:0045617 negative regulation of keratinocyte differentiation
GO:0090303 positive regulation of wound healing
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000071356
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.567312
RefSeq NM_002580 NM_138937 NM_138938
HUGO
OMIM
CCDS CCDS1965
HPRD 01342
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca