Version 5.4
Homo sapiens Gene: CDHR2
Summary
InnateDB Gene IDBG-58956.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CDHR2
Gene Name cadherin-related family member 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000074276
Encoded Proteins
IDBP-58958
cadherin-related family member 2
IDBP-480034
cadherin-related family member 2
IDBP-483909
cadherin-related family member 2
IDBP-477131
cadherin-related family member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the protocadherin family, which represents a subset of the larger cadherin superfamily. The members of the protocadherin family encode non-classical cadherins that function as calcium-dependent cell-cell adhesion molecules. This protocadherin represents a new candidate for tumor suppression. Alternatively spliced transcript variants that encode the same protein have been identified. [provided by RefSeq, Jan 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:176542511-176595974
Strand Forward strand
Band q35.2
Transcripts
ENST00000261944 ENSP00000261944
ENST00000416365
ENST00000510636 ENSP00000424565
ENST00000510124 ENSP00000426838
ENST00000506348 ENSP00000421078
ENST00000513031
ENST00000508085
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 2 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion
GO:0030308 negative regulation of cell growth
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0030054 cell junction
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034918
View Gene Order
ENSBTAG00000025340
Not yet available
Cross-References
SwissProt
TrEMBL D6REJ3
UniProt Splice Variant
Entrez Gene 54825
UniGene Hs.4205
RefSeq NM_001171976 NM_017675 XM_006714887
HUGO HGNC:18231
OMIM
CCDS CCDS34297
HPRD 15103
IMGT
EMBL AC091934
GenPept
RNA Seq Atlas 54825

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca