Version 5.4
Homo sapiens Gene: NPAS1
Summary
InnateDB Gene IDBG-59191.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NPAS1
Gene Name neuronal PAS domain protein 1
Synonyms bHLHe11; MOP5; PASD5
Species Homo sapiens
Ensembl Gene ENSG00000130751
Encoded Proteins
IDBP-382376
neuronal PAS domain protein 1
IDBP-382379
neuronal PAS domain protein 1
IDBP-763767
IDBP-761165
IDBP-765743
IDBP-765029
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. Studies of a related mouse gene suggest that it functions in neurons. The exact function of this gene is unclear, but it may play protective or modulatory roles during late embryogenesis and postnatal development. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:47019820-47045775
Strand Forward strand
Band q13.32
Transcripts
ENST00000439365 ENSP00000398689
ENST00000449844 ENSP00000405290
ENST00000601169
ENST00000602212 ENSP00000469142
ENST00000594670 ENSP00000472075
ENST00000600352
ENST00000602189 ENSP00000472679
ENST00000594257 ENSP00000468871
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0004871 signal transducer activity
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001964 startle response
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007165 signal transduction
GO:0007417 central nervous system development
GO:0042711 maternal behavior
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000001988
View Gene Order
ENSBTAG00000015576
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.79564
RefSeq NM_002517 XM_006723231
HUGO
OMIM
CCDS CCDS12694
HPRD 09136
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca