InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NPAS1

Summary

InnateDB Protein

IDBP-382379.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NPAS1

Protein Name

neuronal PAS domain protein 1

Synonyms

bHLHe11; MOP5; PASD5;

Species

Homo sapiens

Ensembl Protein

ENSP00000405290

InnateDB Gene

IDBG-59191 (NPAS1)

Protein Structure

UniProt Annotation

Function

May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00981}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0004871	signal transducer activity
GO:0005515	protein binding
GO:0046983	protein dimerization activity

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007165	signal transduction
GO:0007417	central nervous system development