Version 5.4
Homo sapiens Gene: SLC39A12
Summary
InnateDB Gene IDBG-59562.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC39A12
Gene Name solute carrier family 39 (zinc transporter), member 12
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000148482
Encoded Proteins
IDBP-59564
solute carrier family 39 (zinc transporter), member 12
IDBP-59568
solute carrier family 39 (zinc transporter), member 12
IDBP-59570
solute carrier family 39 (zinc transporter), member 12
IDBP-587459
solute carrier family 39 (zinc transporter), member 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A12 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:17951839-18043292
Strand Forward strand
Band p12.33
Transcripts
ENST00000377374 ENSP00000366591
ENST00000377371 ENSP00000366588
ENST00000377369 ENSP00000366586
ENST00000539911 ENSP00000440445
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005385 zinc ion transmembrane transporter activity
GO:0046873 metal ion transmembrane transporter activity
Biological Process
GO:0006829 zinc ion transport
GO:0007165 signal transduction
GO:0010975 regulation of neuron projection development
GO:0030001 metal ion transport
GO:0031113 regulation of microtubule polymerization
GO:0055085 transmembrane transport
GO:0071578 zinc ion transmembrane import
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036949
View Gene Order
ENSBTAG00000015525
Not yet available
Cross-References
SwissProt Q504Y0
TrEMBL
UniProt Splice Variant
Entrez Gene 221074
UniGene Hs.350895
RefSeq NM_001282733 NM_001145195 NM_001282734 NM_152725
HUGO HGNC:20860
OMIM 608734
CCDS CCDS60493 CCDS44362 CCDS60494 CCDS7124
HPRD 15384
IMGT
EMBL AC069023 AK055061 AL360231 AL590111 BC035118 BC047635 BC065917 BC094700 BC117323 BC143551
GenPept AAH35118 AAH47635 AAH65917 AAH94700 AAI17324 AAI43552 BAB70848 CAH70123 CAH70124 CAI15903 CAI15904
RNA Seq Atlas 221074

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca