Version 5.4
Homo sapiens Protein: SLC39A12
Summary
InnateDB Protein IDBP-59570.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC39A12
Protein Name solute carrier family 39 (zinc transporter), member 12
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000366586
InnateDB Gene IDBG-59562 (SLC39A12)
Protein Structure
UniProt Annotation
Function Acts as a zinc-influx transporter (Potential). May be partly involved in the outbreak of schizophrenia. {ECO:0000305}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in brain and eye. {ECO:0000269PubMed:12107410, ECO:0000269PubMed:15342556}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005385 zinc ion transmembrane transporter activity
GO:0046873 metal ion transmembrane transporter activity
Biological Process
GO:0006829 zinc ion transport
GO:0007165 signal transduction
GO:0010975 regulation of neuron projection development
GO:0030001 metal ion transport
GO:0031113 regulation of microtubule polymerization
GO:0055085 transmembrane transport
GO:0071578 zinc ion transmembrane import
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR003689 Zinc/iron permease
PFAM PF02535
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q504Y0
PhosphoSite PhosphoSite-Q504Y0
TrEMBL F5GX72
UniProt Splice Variant
Entrez Gene 221074
UniGene Hs.350895
RefSeq NP_001138667
HUGO HGNC:20860
OMIM 608734
CCDS CCDS44362
HPRD 15384
IMGT
EMBL AC069023 AK055061 AL360231 AL590111 BC035118 BC047635 BC065917 BC094700 BC117323 BC143551
GenPept AAH35118 AAH47635 AAH65917 AAH94700 AAI17324 AAI43552 BAB70848 CAH70123 CAH70124 CAI15903 CAI15904

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca