Version 5.4
Homo sapiens Gene: RCE1
Summary
InnateDB Gene IDBG-59671.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RCE1
Gene Name RCE1 homolog, prenyl protein protease (S. cerevisiae)
Synonyms FACE2; RCE1A; RCE1B
Species Homo sapiens
Ensembl Gene ENSG00000173653
Encoded Proteins
IDBP-59673
RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
IDBP-604373
RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
IDBP-604374
RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
IDBP-604375
RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes an integral membrane protein which is classified as a member of the metalloproteinase family. This enzyme is thought to function in the maintenance and processing of CAAX-type prenylated proteins. [provided by RefSeq, Jul 2008]
This gene encodes an integral membrane protein which is classified as a member of the metalloproteinase family. This enzyme is thought to function in the maintenance and processing of CAAX-type prenylated proteins. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:66842835-66846546
Strand Forward strand
Band q13.2
Transcripts
ENST00000309657 ENSP00000309163
ENST00000533277
ENST00000524506 ENSP00000436600
ENST00000524849 ENSP00000436300
ENST00000530610
ENST00000534822
ENST00000532775
ENST00000525356 ENSP00000435409
ENST00000534645
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004197 cysteine-type endopeptidase activity
GO:0004222 metalloendopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0071586 CAAX-box protein processing
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024889
View Gene Order
ENSBTAG00000019696
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00900
Terpenoid backbone biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.654972
RefSeq NM_001032279 NM_005133
HUGO
OMIM
CCDS CCDS8151
HPRD 07289
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca