Version 5.4
Homo sapiens Gene: TAOK3
Summary
InnateDB Gene IDBG-59760.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TAOK3
Gene Name TAO kinase 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000135090
Encoded Proteins
IDBP-245456
TAO kinase 3
IDBP-383970
TAO kinase 3
IDBP-596769
TAO kinase 3
IDBP-586169
TAO kinase 3
IDBP-588234
TAO kinase 3
IDBP-600475
TAO kinase 3
IDBP-596924
TAO kinase 3
IDBP-596633
TAO kinase 3
IDBP-588407
TAO kinase 3
IDBP-600159
TAO kinase 3
IDBP-589776
TAO kinase 3
IDBP-583522
TAO kinase 3
IDBP-596877
TAO kinase 3
IDBP-595629
TAO kinase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:118149801-118372945
Strand Reverse strand
Band q24.23
Transcripts
ENST00000392533 ENSP00000376317
ENST00000419821 ENSP00000416374
ENST00000543709
ENST00000537305
ENST00000536979 ENSP00000441932
ENST00000537952 ENSP00000443834
ENST00000537569
ENST00000540561 ENSP00000443487
ENST00000537822 ENSP00000439620
ENST00000536584
ENST00000538601 ENSP00000437389
ENST00000535570 ENSP00000443465
ENST00000541186 ENSP00000438820
ENST00000541878 ENSP00000444057
ENST00000542902 ENSP00000440315
ENST00000542532 ENSP00000441071
ENST00000541786 ENSP00000442541
ENST00000539872 ENSP00000438766
ENST00000542692
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 7 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004860 protein kinase inhibitor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0000165 MAPK cascade
GO:0000186 activation of MAPKK activity
GO:0006281 DNA repair
GO:0006468 protein phosphorylation
GO:0006469 negative regulation of protein kinase activity
GO:0006974 cellular response to DNA damage stimulus
GO:0016310 phosphorylation
GO:0031572 G2 DNA damage checkpoint
GO:0032874 positive regulation of stress-activated MAPK cascade
GO:0043507 positive regulation of JUN kinase activity
GO:0046329 negative regulation of JNK cascade
GO:0046330 positive regulation of JNK cascade
GO:0046777 protein autophosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000061288
View Gene Order
ENSBTAG00000012550
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04010
MAPK signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.644420
RefSeq NM_016281
HUGO
OMIM
CCDS CCDS9188
HPRD 11620
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca