Version 5.4
Mus musculus Gene: Synj2bp
Summary
InnateDB Gene IDBG-605394.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Synj2bp
Gene Name synaptojanin 2 binding protein
Synonyms AA409442; ActRIP4; ARIP2; ARIP2a; D12Wsu118e; OMP25
Species Mus musculus
Ensembl Gene ENSMUSG00000090935
Encoded Proteins
IDBP-252264
synaptojanin 2 binding protein
IDBP-621044
synaptojanin 2 binding protein
IDBP-621047
synaptojanin 2 binding protein
IDBP-621054
synaptojanin 2 binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000213463:
This locus represents naturally occurring read-through transcription between the neighboring SYNJ2BP (synaptojanin 2 binding protein) and COX16 (COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)) genes on chromosome 14. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:81497941-81532911
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000019829
ENSMUST00000114201 ENSMUSP00000109839
ENSMUST00000163402 ENSMUSP00000129224
ENSMUST00000164431 ENSMUSP00000129053
ENSMUST00000169158 ENSMUSP00000130691
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0070699 type II activin receptor binding
Biological Process
GO:0002092 positive regulation of receptor internalization
GO:0006897 endocytosis
GO:0032926 negative regulation of activin receptor signaling pathway
GO:0032927 positive regulation of activin receptor signaling pathway
GO:0048312 intracellular distribution of mitochondria
GO:2000010 positive regulation of protein localization to cell surface
Cellular Component
GO:0005739 mitochondrion
GO:0009986 cell surface
GO:0031307 integral component of mitochondrial outer membrane
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000213463
View Gene Order
ENSBTAG00000007586
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.279603 Mm.401431 Mm.408395 Mm.417572
RefSeq NM_025292
OMIM
CCDS CCDS26021
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca