Version 5.4
Homo sapiens Gene: VEZF1
Summary
InnateDB Gene IDBG-60556.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VEZF1
Gene Name vascular endothelial zinc finger 1
Synonyms DB1; ZNF161
Species Homo sapiens
Ensembl Gene ENSG00000136451
Encoded Proteins
IDBP-60558
vascular endothelial zinc finger 1
IDBP-764040
IDBP-764408
IDBP-763152
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. ZNF161 is a C2H2-type zinc finger protein (Koyano-Nakagawa et al., 1994 [PubMed 8035792]). See MIM 603971 for general information on zinc finger proteins.[supplied by OMIM, Sep 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:57971547-57988259
Strand Reverse strand
Band q22
Transcripts
ENST00000258963 ENSP00000258963
ENST00000584396 ENSP00000464687
ENST00000581208 ENSP00000462337
ENST00000583932 ENSP00000463631
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0001525 angiogenesis
GO:0001885 endothelial cell development
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0006968 cellular defense response
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000018377
View Gene Order
ENSBTAG00000004193
Not yet available
Cross-References
SwissProt
TrEMBL J3QSH4
UniProt Splice Variant
Entrez Gene 7716
UniGene Hs.463569 Hs.592377 Hs.710664 Hs.714434
RefSeq NM_007146 XM_005257643 XM_005257644
HUGO HGNC:12949
OMIM 606747
CCDS CCDS32687
HPRD 08416
IMGT
EMBL AC015813
GenPept
RNA Seq Atlas 7716

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca