Version 5.4
Mus musculus Gene: Hspa1a
Summary
InnateDB Gene IDBG-606688.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hspa1a
Gene Name heat shock protein 1A
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000091971
Encoded Proteins
IDBP-175334
heat shock protein 1A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:34969190-34972156
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000087328 ENSMUSP00000084586
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 1 [view]
Protein-DNA 6 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0000902 cell morphogenesis
GO:0006402 mRNA catabolic process
GO:0006986 response to unfolded protein
GO:0008285 negative regulation of cell proliferation
GO:0030308 negative regulation of cell growth
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016607 nuclear speck
GO:0048471 perinuclear region of cytoplasm
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_198687
Regulation of mRNA stability by proteins that bind AU-rich elements pathway
REACT_188957
Cellular responses to stress pathway
REACT_198693
AUF1 (hnRNP D0) destabilizes mRNA pathway
REACT_213550
HSF1-dependent transactivation pathway
REACT_224790
Cellular response to heat stress pathway
REACT_223784
Attenuation phase pathway
REACT_233572
Gene Expression pathway
REACT_222185
Regulation of HSF1-mediated heat shock response pathway
KEGG
mmu04612
Antigen processing and presentation pathway
mmu04010
MAPK signaling pathway pathway
mmu05020
Prion diseases pathway
mmu04144
Endocytosis pathway
mmu03040
Spliceosome pathway
mmu04141
Protein processing in endoplasmic reticulum pathway
mmu05145
Toxoplasmosis pathway
INOH
PID NCI
Cross-References
SwissProt Q61696
TrEMBL Q3TU85
UniProt Splice Variant
Entrez Gene 193740
UniGene Mm.6388
RefSeq NM_010479
OMIM
CCDS CCDS50080
HPRD
IMGT
MGI ID MGI:96244
MGI Symbol Hspa1a
EMBL AF109906 AK160912 BC054782 BC151107 BC151109 BC157921 CH466666 M12571 M12572 M76613
GenPept AAA57233 AAA57234 AAA57235 AAC84169 AAH54782 AAI51108 AAI51110 AAI57922 BAE36086 EDL26710
RNA Seq Atlas 193740

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca