Version 5.4
Homo sapiens Gene: OASL
Summary
InnateDB Gene IDBG-61209.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OASL
Gene Name 2'-5'-oligoadenylate synthetase-like
Synonyms OASLd; p59 OASL; p59-OASL; p59OASL; TRIP-14; TRIP14
Species Homo sapiens
Ensembl Gene ENSG00000135114
Encoded Proteins
IDBP-61211
2'-5'-oligoadenylate synthetase-like
IDBP-61213
2'-5'-oligoadenylate synthetase-like
IDBP-584160
2'-5'-oligoadenylate synthetase-like
IDBP-813512
2'-5'-oligoadenylate synthetase-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:121020292-121039242
Strand Reverse strand
Band q24.31
Transcripts
ENST00000257570 ENSP00000257570
ENST00000339275 ENSP00000341125
ENST00000543677 ENSP00000444127
ENST00000620239 ENSP00000479512
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016740 transferase activity
GO:0044822 poly(A) RNA binding
GO:0046966 thyroid hormone receptor binding
Biological Process
GO:0006955 immune response
GO:0008152 metabolic process
GO:0009615 response to virus
GO:0019221 cytokine-mediated signaling pathway
GO:0045071 negative regulation of viral genome replication
GO:0051607 defense response to virus
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060337 type I interferon signaling pathway
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000041827
View Gene Order
ENSBTAG00000003297
Not yet available
Pathways
NETPATH
REACTOME
REACT_25162
Interferon alpha/beta signaling pathway
REACT_25078
Interferon gamma signaling pathway
REACT_75790
Cytokine Signaling in Immune system pathway
REACT_25229
Interferon Signaling pathway
REACT_6900
Immune System pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 8638
UniGene
RefSeq NM_001261825 NM_003733 NM_198213
HUGO HGNC:8090
OMIM 603281
CCDS CCDS73536 CCDS9211 CCDS9212
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas 8638

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca