Version 5.4
Homo sapiens Gene: SKA2
Summary
InnateDB Gene IDBG-61594.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SKA2
Gene Name spindle and kinetochore associated complex subunit 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000182628
Encoded Proteins
IDBP-61596
spindle and kinetochore associated complex subunit 2
IDBP-382450
spindle and kinetochore associated complex subunit 2
IDBP-763367
IDBP-762079
IDBP-759740
IDBP-757692
IDBP-763511
IDBP-758760
IDBP-761911
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:59109951-59155269
Strand Reverse strand
Band q22
Transcripts
ENST00000330137 ENSP00000333433
ENST00000437036 ENSP00000411231
ENST00000584089 ENSP00000463315
ENST00000578519 ENSP00000464558
ENST00000581068 ENSP00000462220
ENST00000583927
ENST00000583380 ENSP00000462574
ENST00000580541 ENSP00000462197
ENST00000583976 ENSP00000463167
ENST00000578105 ENSP00000462918
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008017 microtubule binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0007059 chromosome segregation
GO:0007067 mitotic nuclear division
GO:0031110 regulation of microtubule polymerization or depolymerization
GO:0051301 cell division
Cellular Component
GO:0000940 condensed chromosome outer kinetochore
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005876 spindle microtubule
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020492
View Gene Order
ENSBTAG00000021680
Not yet available
Pathways
NETPATH
REACTOME
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_1275
Mitotic Anaphase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.463607 Hs.619211
RefSeq NM_001100595 NM_182620
HUGO
OMIM
CCDS CCDS45747 CCDS45748
HPRD 13306
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca