Version 5.4
Homo sapiens Gene: MLXIP
Summary
InnateDB Gene IDBG-62150.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MLXIP
Gene Name MLX interacting protein
Synonyms bHLHe36; MIR; MONDOA
Species Homo sapiens
Ensembl Gene ENSG00000175727
Encoded Proteins
IDBP-62152
MLX interacting protein
IDBP-62154
MLX interacting protein
IDBP-591230
MLX interacting protein
IDBP-590502
MLX interacting protein
IDBP-593326
MLX interacting protein
IDBP-583893
MLX interacting protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary MONDOA forms heterodimers with MLX (MIM 602976) that can bind to and activate transcription from CACGTG E boxes (Billin et al., 2000 [PubMed 11073985]).[supplied by OMIM, Mar 2008]
This gene encodes a protein that functions as part of a heterodimer to activate transcription. The encoded protein forms a heterodimer with Max-like protein X (MLX) and is involved in the regulation of genes in response to cellular glucose levels. [provided by RefSeq, Mar 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:122078722-122147347
Strand Forward strand
Band q24.31
Transcripts
ENST00000319080 ENSP00000312834
ENST00000377037 ENSP00000366236
ENST00000366272 ENSP00000445891
ENST00000535430 ENSP00000438206
ENST00000539861
ENST00000535876
ENST00000538061
ENST00000538698 ENSP00000440769
ENST00000541750
ENST00000535996
ENST00000542417 ENSP00000444507
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006913 nucleocytoplasmic transport
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005741 mitochondrial outer membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000038342
View Gene Order
ENSBTAG00000004189
Not yet available
Cross-References
SwissProt Q9HAP2
TrEMBL C9JBQ4 F5H0V4 F5H321
UniProt Splice Variant
Entrez Gene 22877
UniGene Hs.614194 Hs.721711 Hs.731847
RefSeq NM_014938 XM_006719292 XM_006719293
HUGO HGNC:17055
OMIM 608090
CCDS CCDS73540
HPRD
IMGT
EMBL AB020674 AC048338 AC130894 AC156455 AC190384 AC205581 AF245480 AF245481 AF312918 BC017656 BC028309 BC039704 BC151841
GenPept AAG34121 AAH17656 AAH28309 AAH39704 AAI51842 AAL55689 AAL55690 BAA74890
RNA Seq Atlas 22877

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca