Version 5.4
Homo sapiens Gene: GFPT2
Summary
InnateDB Gene IDBG-62273.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GFPT2
Gene Name glutamine-fructose-6-phosphate transaminase 2
Synonyms GFAT2
Species Homo sapiens
Ensembl Gene ENSG00000131459
Encoded Proteins
IDBP-62275
glutamine-fructose-6-phosphate transaminase 2
IDBP-476071
glutamine-fructose-6-phosphate transaminase 2
IDBP-477658
glutamine-fructose-6-phosphate transaminase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 5:180300690-180353387
Strand Reverse strand
Band q35.3
Transcripts
ENST00000253778 ENSP00000253778
ENST00000520165
ENST00000510122
ENST00000518906 ENSP00000431125
ENST00000518185
ENST00000518158
ENST00000503546
ENST00000503228 ENSP00000422771
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GO:0030246 carbohydrate binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006002 fructose 6-phosphate metabolic process
GO:0006048 UDP-N-acetylglucosamine biosynthetic process
GO:0006112 energy reserve metabolic process
GO:0006488 dolichol-linked oligosaccharide biosynthetic process
GO:0006541 glutamine metabolic process
GO:0008152 metabolic process
GO:0016051 carbohydrate biosynthetic process
GO:0018279 protein N-linked glycosylation via asparagine
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020363
View Gene Order
ENSBTAG00000002215
Not yet available
Pathways
NETPATH
REACTOME
REACT_22394
Synthesis of UDP-N-acetyl-glucosamine pathway
REACT_22433
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_22161
Post-translational protein modification pathway
REACT_22387
Synthesis of substrates in N-glycan biosythesis pathway
REACT_17015
Metabolism of proteins pathway
KEGG
hsa00520
Amino sugar and nucleotide sugar metabolism pathway
hsa00250
Alanine, aspartate and glutamate metabolism pathway
INOH
INOH website
Aminosugars metabolism pathway
INOH website
Fructose Mannose metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.696497
RefSeq NM_005110
HUGO
OMIM
CCDS CCDS43411
HPRD 04842
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca