Version 5.4
Homo sapiens Gene: HCAR2
Summary
InnateDB Gene IDBG-62724.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HCAR2
Gene Name hydroxycarboxylic acid receptor 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000182782
Encoded Proteins
IDBP-62726
hydroxycarboxylic acid receptor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:122701293-122703343
Strand Reverse strand
Band q24.31
Transcripts
ENST00000328880 ENSP00000375066
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0070553 nicotinic acid receptor activity
Biological Process
GO:0001781 neutrophil apoptotic process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0033031 positive regulation of neutrophil apoptotic process
GO:0050995 negative regulation of lipid catabolic process
GO:0070165 positive regulation of adiponectin secretion
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000045502
View Gene Order
ENSBTAG00000047904
Not yet available
Pathways
NETPATH
REACTOME
REACT_19231
G alpha (i) signalling events pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_163785
Hydroxycarboxylic acid-binding receptors pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8TDS4
TrEMBL
UniProt Splice Variant
Entrez Gene 338442
UniGene Hs.524812
RefSeq NM_177551
HUGO HGNC:24827
OMIM 609163
CCDS CCDS9235
HPRD
IMGT
EMBL AB065876 AB083632 AY148884 BC027965 BC056419 EU012026
GenPept AAH27965 AAH56419 AAN71621 ABS29270 BAB89345 BAC06094
RNA Seq Atlas 338442

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca