Version 5.4
Mus musculus Gene: Niacr1
Summary
InnateDB Gene IDBG-200062.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Niacr1
Gene Name niacin receptor 1
Synonyms Gpr109a; Gpr109b; HM74; mHM74b; Niacr1; PUMA-G; Pumag
Species Mus musculus
Ensembl Gene ENSMUSG00000045502
Encoded Proteins
IDBP-200064
niacin receptor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000182782:
Gene Information
Type Protein coding
Genomic Location Chromosome 5:123863570-123865516
Strand Reverse strand
Band F
Transcripts
ENSMUST00000057145 ENSMUSP00000054104
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001614 purinergic nucleotide receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0005525 GTP binding
GO:0070553 nicotinic acid receptor activity
Biological Process
GO:0006915 apoptotic process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0033031 positive regulation of neutrophil apoptotic process
GO:0035590 purinergic nucleotide receptor signaling pathway
GO:0050995 negative regulation of lipid catabolic process
GO:0070165 positive regulation of adiponectin secretion
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000182782
View Gene Order
ENSBTAG00000047904
Not yet available
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_261161
Class A/1 (Rhodopsin-like receptors) pathway
REACT_231468
GPCR ligand binding pathway
REACT_198712
Hydroxycarboxylic acid-binding receptors pathway
REACT_250376
G alpha (i) signalling events pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19231
G alpha (i) signalling events pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_163785
Hydroxycarboxylic acid-binding receptors pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9EP66
TrEMBL Q0VBA6
UniProt Splice Variant
Entrez Gene 80885
UniGene Mm.440567 Mm.486809
RefSeq NM_030701
OMIM
CCDS CCDS19668
HPRD
IMGT
MGI ID MGI:1933383
MGI Symbol Hcar2
EMBL AJ300198 AJ300199 AK150795 BC120715 BC125296 CH466529
GenPept AAI20716 AAI25297 BAE29858 CAC17790 CAC17791 EDL19619
RNA Seq Atlas 80885

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca